- Sortie
- Sortilege
- Sorus
- Sos
- Soteriology
- Souffle
- Soul food
- Soulfulness
- Soulless
- Sound bow
- Sounding board
- Sounding-line
- Sounding-rocket
- Soundings
- Soupcon
- Soupy
- Sour grapes
- Sourpuls
- Sourpuss
- Soursop
- Souse
- Soused
- South eastern
- South sea
- South-wester
- Southerly
- Southern
- Southernmost
- Southward
- Sovereignty
- Sovietize
- Sow
- Sow-drunk
- Sower
- Sozzled
- Space
- Space between the legs
- Space flight
- Space probe
- Space-ship
- Spade
- Spaghetti
- Spandex
- Spaniel
- Spanish
- Spank
- Spanker
- Spanner
- Spare
- Sparing, sparingly
- Sparingly
- Spark
- Sparkish
- Sparred
- Spastic
- Spate
- Spatterdash
- Spattle
- Speak for
- Speak for itself
- Speak ones mind
- Speak out
- Speakable
- Speaker
- Speaker phone
- Speaker ship
- Speaking acquaintance
- Speaking tube
- Spear
- Special
- Special examination
- Special correspondent
- Special economic zone
- Specialism
- Specialist
- Speciality
- Specialization
- Specialize
- Specialty
- Specificate
- Specification
- Specificity
- Specious
- Speciousity
- Speckled
- Spectator
- Spectral
- Spectrally
- Spectrum
- Speculation
- Speculativeness
- Speculator
- Speech
- Speechify
- Speedily
- Speedway
- Speeler
- Speleology
- Spelling check
- Spelt